Everything on Natural Health & Remedies →
Primary documents
- A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial (2015)
Peer-Reviewed Study · 2015
Pärtty A, Kalliomäki M, Wacklin P, Salminen S, Isolauri E
Seventy-five infants originally randomized to Lactobacillus rhamnosus GG or placebo during their first six months were followed for 13 years. This was an infancy-intervention follow-up, not…
- A potential natural treatment for attention-deficit/hyperactivity disorder: evidence from a national study (2004)
Peer-Reviewed Study · 2004
Kuo FE, Taylor AF
Analysis of 452 usable parent surveys from a national Internet-based nonprobability sample found greener outdoor settings associated with greater parent-rated symptom reduction than built outdoor or…
- ADHD Diagnosis and Drug Use Estimates in France: A Case for Using Health Care Insurance Data (2021)
Peer-Reviewed Study · 2021
Ponnou S, Théry B, Viellard M, et al.
Using French health-insurance and medication-safety data, the authors estimated ADHD identification around 0.3% among children ages 6–11. The abstract contrasts that estimate with an earlier 3.5%–5.6%…
- America’s Children and the Environment, Third Edition: Lead — Biomonitoring Updates (2022)
Government Record · 2022
U.S. Environmental Protection Agency
EPA’s analysis of NHANES reports a 95% decline in median blood lead among children ages 1–5 from 1976–1980 to 2015–2016. The 95th percentile fell from 29…
- Attention deficit hyperactivity disorder: diagnosis and management — Overview (2026)
Government Record · 2026
National Institute for Health and Care Excellence
NICE last reviewed NG87 on July 23, 2026 and decided not to update the recommendations on adapted trauma-focused treatment. The guideline will be reviewed again if…
- Attention deficit hyperactivity disorder: diagnosis and management — Recommendations (2019)
Government Record · 2019
National Institute for Health and Care Excellence
NICE requires persistent significant impairment after environmental modifications have been implemented and reviewed before medication for children aged five and over, with information discussion and baseline…
- Can the Prevalence of ADHD Really be 0.3%? (2021)
Peer-Reviewed Study · 2021
Ramus F, Peyre H
PubMed identifies a published comment challenging the very low French estimate, but expressly provides no abstract.
- CDC Updates Blood Lead Reference Value (2021)
Government Record · 2021
U.S. Centers for Disease Control and Prevention
CDC’s current blood lead reference value is 3.5 µg/dL, based on the 97.5th percentile for U.S. children ages 1–5 in NHANES 2015–2018. CDC states that no…
- Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents (2019)
Peer-Reviewed Study · 2019
Wolraich ML, Hagan JF Jr, Allan C, et al.; AAP Subcommittee on Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
The AAP recommends evidence-based parent training in behavior management and/or behavioral classroom intervention first for preschool-aged children, when available. Methylphenidate may be considered if behavioral interventions…
- Color Additives – Information for Consumers (2026)
Government Record · 2026
U.S. Food and Drug Administration
FDA’s current position is that most children have no adverse effects while certain children may be sensitive. It repeats that the 2011 committee did not establish…
- Color Additives and Behavioral Effects in Children (2019)
Government Record · 2019
Science Board to the FDA
FDA’s official account states that its 2011 Food Advisory Committee did not establish a causal link and recommended further research plus a comprehensive exposure assessment.
- Effects of a restricted elimination diet on the behaviour of children with attention-deficit hyperactivity disorder (INCA study): a randomised controlled trial (2011)
Peer-Reviewed Study · 2011
Pelsser LM, Frankena K, Toorman J, et al.
INCA randomized 100 children aged 4–8 to five weeks of restricted elimination diet or healthy-diet instructions, followed by double-blind food challenges in responders. Masked between-group ARS…
- Empirically derived dietary patterns and food groups intake in relation with Attention Deficit/Hyperactivity Disorder (ADHD): A systematic review and meta-analysis (2020)
Peer-Reviewed Study · 2020
Shareghfarid E, Sangsefidi ZS, Salehi-Abargouei A, Hosseinzadeh M
Six dietary-pattern studies totaling 8,816 participants produced pooled associations for Western, junk-food, and healthy patterns. This is the closest located quantitative match, but it is a…
- FDA to Revoke Authorization for the Use of Red No. 3 in Food and Ingested Drugs (2025)
Government Record · 2025
U.S. Food and Drug Administration
FDA revoked Red No. 3 authorization after a 2022 petition because the Delaney Clause applies to color additives shown to induce cancer in animals. FDA also…
- Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial (2007)
Peer-Reviewed Study · 2007
McCann D, Barrett A, Cooper A, et al.
Randomized double-blind placebo-controlled crossover study of 153 three-year-olds and 144 eight-/nine-year-olds. Mix A significantly increased global hyperactivity, but the challenge combined colors with sodium benzoate and…
- Fourth National Report on Human Exposure to Environmental Chemicals, Updated Tables, January 2019
Government Record · 2019
U.S. Centers for Disease Control and Prevention
The CDC landing record identifies the national biomonitoring report and its January 2019 updated tables. The underlying NHANES series covers 1999–2000 through 2015–2016, with random subsamples…
- Glyphosate and neurological outcomes: A systematic literature review of animal studies (2022)
Peer-Reviewed Study · 2022
Moser VC, Batsel B, Bailey J, et al.
This review assessed 27 in vivo mammalian studies, rated 11 unreliable, and found only seven acceptable investigations of glyphosate alone. Motor activity was the most consistently…
- Health Effects Assessment: Potential Neurobehavioral Effects of Synthetic Food Dyes in Children (2021)
Government Record · 2021
California Office of Environmental Health Hazard Assessment
OEHHA’s 311-page assessment concludes that synthetic food dyes are associated with adverse neurobehavioral effects in sensitive children, including children with and without pre-existing behavioral disorders.
- HHS, FDA to Phase Out Petroleum-Based Synthetic Dyes in Nation’s Food Supply (2025)
Government Record · 2025
U.S. Department of Health and Human Services and U.S. Food and Drug Administration
The April 2025 announcement described a national initiative and voluntary work with industry to eliminate Green No. 3, Red No. 40, Yellow No. 5, Yellow No.…
- Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis (2015)
Peer-Reviewed Study · 2015
Yano JM, Yu K, Donaldson GP, et al.
Using germ-free and colonized mice, cell culture, and mouse/human microbiota experiments, the study found that indigenous spore-forming bacteria regulate host peripheral serotonin biosynthesis. It did not…
- Meta-Analysis of Attention-Deficit/Hyperactivity Disorder or Attention-Deficit/Hyperactivity Disorder Symptoms, Restriction Diet, and Synthetic Food Color Additives (2012)
Peer-Reviewed Study · 2012
Nigg JT, Lewis K, Edinger T, Falk M
The meta-analysis found a small restriction-diet effect and small food-color effects that varied by informant, study quality, and publication-bias adjustment. Parent-reported food-color g was 0.18 and…
- Mindfulness-based school interventions: A systematic review of outcome evidence quality by study design (2022)
Peer-Reviewed Study · 2022
Phan ML, Renshaw TL, Caramanico J, et al.
This systematic review found promising evidence for some attention, ADHD-behavior, anxiety, executive-function, and conduct outcomes, while emphasizing variation in study quality. It did not supply the…
- Omega-3 fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology: systematic review and meta-analysis (2011)
Peer-Reviewed Study · 2011
Bloch MH, Qawasmi A
Ten randomized placebo-controlled trials involving 699 children yielded a small significant benefit, with overall effect size 0.31 (95% CI 0.16–0.47). The authors expressly characterized efficacy as…
- Physical Activity Guidelines for Americans, 2nd edition (2018)
Government Record · 2018
U.S. Department of Health and Human Services
The federal guidelines recommend at least 60 minutes of moderate-to-vigorous physical activity daily for children and adolescents ages 6–17. This is a general health guideline, not…