Electronic Support for Public Health—Vaccine Adverse Event Reporting System (ESP:VAERS), Final Report (2010)

Other · Lazarus R, Klompas M, et al., Harvard Pilgrim Health Care (AHRQ grant R18 HS017045) · December 1, 2010

The source of the ubiquitous 'less than 1% of vaccine adverse events are reported' claim. Nuances: (1) the <1% sentence is a literature-based estimate in the introduction, not a measurement of this project; (2) the project's own automated surveillance of 1.4 million vaccine doses to 376,452 individuals flagged 35,570 possible reactions (2.6%); (3) the planned system-performance evaluation was never completed — 'the necessary CDC contacts were no longer available and the CDC consultants… were no longer responsive to our multiple requests'; (4) AHRQ's disclaimer states findings are the authors' own, not an official AHRQ/HHS position.

Likewise, fewer than 1% of vaccine adverse events are reported.

Final report, introduction (grant period 12/01/2007-09/30/2010)

The source of the ubiquitous 'less than 1% of vaccine adverse events are reported' claim. Nuances: (1) the <1% sentence is a literature-based estimate in the introduction, not a measurement of this project; (2) the project's own automated surveillance of 1.4 million vaccine doses to 376,452 individuals flagged 35,570 possible reactions (2.6%); (3) the planned system-performance evaluation was never completed — 'the necessary CDC contacts were no longer available and the CDC consultants… were no longer responsive to our multiple requests'; (4) AHRQ's disclaimer states findings are the authors' own, not an official AHRQ/HHS position. Contractor report funded by AHRQ; copyright status unclear. The <1% figure is real but is an inherited estimate;

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