York systematic review underpinning the Cass Review: 50 studies of puberty suppression, only 1 rated high quality. Finds no conclusions possible on gender dysphoria, mental/psychosocial health or cognitive development; bone health and height may be compromised.
No conclusions can be drawn about the impact on gender dysphoria, mental and psychosocial health or cognitive development. Bone health and height may be compromised during treatment.
York systematic review underpinning the Cass Review: 50 studies of puberty suppression, only 1 rated high quality. Finds no conclusions possible on gender dysphoria, mental/psychosocial health or cognitive development; bone health and height may be compromised. Peer-reviewed systematic review (study design: systematic review of 50 observational studies; no RCTs exist in this field).